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Chronic mitral regurgitation by Doppler echocardiography

Native valves
Flowchart: Chronic mitral regurgitation by Doppler echocardiography. A text version follows the figure.
Related:Quick reference 12: Mitral regurgitation
Text of this figure
  • Chronic mitral regurgitation by Doppler echocardiography
  • Yes, mild*
  • Yes, severe**
  • **
  • 2–3
  • criteria
  • 2–3
  • criteria
  • ≥4 criteria
  • Definitely mild
  • ≥4 criteria
  • Definitely severe
  • 3 specific criteria
  • for severe MR or
  • elliptical orifice
  • Chronic mitral regurgitation by Doppler echocardiography
  • Does MR meet specific criteria for
  • mild or severe MR?
  • Specific criteria for mild MR
  • • Small, narrow central jet
  • • VCW ≤0.3 cm
  • • PISA radius absent or ≤0.3 cm at Nyquist
  • 30–40 cm/s
  • • Mitral A-wave dominant inflow
  • • Soft or incomplete jet by CW Doppler
  • • Normal LV and LA size
  • Specific criteria for severe MR
  • • Flail leaflet
  • • VCW ≥0.7 cm
  • • PISA radius ≥1.0 cm at Nyquist 30–40 cm/s
  • • Central large jet >50% of LA area
  • • Pulmonary vein systolic flow reversal
  • • Enlarged LV with normal function
  • Intermediate values:
  • MR probably moderate
  • Perform quantitative methods whenever possible
  • to refine assessment
  • EROA <0.2 cm²
  • RVol <30 mL
  • RF <30%
  • MR Grade I
  • EROA 0.2–0.29 cm²
  • RVol 30–44 mL
  • RF 30–39%
  • MR Grade II
  • EROA 0.30–0.39 cm²
  • RVol 45–59 mL
  • RF 40–49%
  • MR Grade III
  • EROA ≥0.4 cm²
  • RVol ≥60 mL¶
  • RF ≥50%
  • MR Grade IV
  • Mild MR
  • Moderate MR
  • Severe MR
  • • Poor TTE quality or low confidence in measured Doppler parameters
  • • Discordant quantitative and qualitative parameters and/or clinical data
  • Indeterminate MR
  • Consider further testing:
  • TEE or CMR for quantitation
  • * Beware of underestimation of MR severity in eccentric, wall-impinging jets; quantitation is advised.
  • ** All values for EROA by PISA assume holosystolic MR; single-frame EROA by PISA and VCW overestimate non-holosystolic MR.
  • ¶ Regurgitant volume for severe MR may be lower in low-flow conditions.
  • Source: Recommendations for Noninvasive Evaluation of Native Valvular Regurgitation: A Report from the American Society of Echocardiography Developed in Collaboration with the Society for Cardiovascular
  • Magnetic Resonance (2017), Figure 18.
  • Please read the full document from the ASE.

Redrawn as a flowchart from the published document named in the figure. Read the full document for context and the figures' complete notes.