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Steps for diagnosing LV diastolic dysfunction

Atria and diastolic function
Flowchart: Steps for diagnosing LV diastolic dysfunction. A text version follows the figure.
Related:Quick reference 5: Diastolic function and filling pressures
Text of this figure
  • Steps for diagnosing LV diastolic dysfunction
  • STEP 1
  • Assess e′ as marker of
  • impaired
  • LV relaxation
  • • e′ septal ≤6 cm/s or
  • • lateral ≤7 or
  • • average ≤6.5*
  • STEP 2
  • Assess markers of LA/LV
  • remodeling and elevated LAP
  • • Average E/e′ >14
  • • LARS ≤18%
  • • E/A ≤0.8*, or ≥2
  • • LAVI >34 mL/m² ¶
  • Diastolic dysfunction present if:
  • • e′ reduced & 1 or more
  • markers in Step 2 present or
  • • e′ preserved, but 2 or more
  • markers in Step 2 present
  • * Can also consider age-specific cutoff values to identify abnormally reduced e′ velocity
  • or abnormally reduced E/A ratio.
  • LAVI: after excluding LA enlargement in athletes, or due to anemia, atrial fibrillation
  • or flutter, and mitral valve disease.
  • ¶ Another finding consistent with diastolic dysfunction: LV mass index >95 g/m² in women
  • or 115 g/m² in men, after exclusion of increased LV mass in athletes.
  • Source: Recommendations for the Evaluation of Left Ventricular Diastolic Function by Echocardiography and for Heart Failure With Preserved Ejection Fraction
  • Diagnosis: An Update From the American Society of Echocardiography (2025), Figure 2.
  • Please read the full document from the ASE.

Redrawn as a flowchart from the published document named in the figure. Read the full document for context and the figures' complete notes.